Cultural mission

The laboratory promotes research on the role of Adapted Motor Activity in the prevention and treatment of Chronic Noncommunicable Diseases (NCDs).
The Laboratory is an integral part of an inter-university working group for the implementation of outreach and research programs in the field of exercise in oncology (IGEO – Italian Group on Exercise Oncology).

Main lines of research

• Adapted motor activity in cancer patients;
• Adapted motor activity in patients with renal failure;
• Adapted motor activity in neurological patients;
• Adapted motor activity for the prevention and treatment of osteoporosis in women of menopausal age;
• Adapted activity in people with transplantation;
• Adapted physical activity in patient with rheumatic diseases.

Laboratory staff have developed special expertise in the development and delivery of online adapted physical activity protocols.

Instrumentation/technology

The Laboratory has the following equipment for functional assessment: Handgrip – Jamar Plus, Handy 3000 Impedance Meter – DS Medica s.r.l., QUARK RMR Indirect Calorimetry by COSMED, Polar Heart Rate Monitors, ECG SE 1515 DX12 – PC Based complete with Stress, MONARK BIKE CYCLOERGOMETER 939E S/N WBK274934, Woodway Treadmill, Dynamometer Force Sensor Kit, Chronojump.

Publications and articles

Moulton C, Murri A, Benotti G, Fantini C, Duranti G, Ceci R, Grazioli E, Cerulli C, Sgrò P, Rossi C, Magno S, Di Luigi L, Caporossi D, Parisi A, Dimauro I. The impact of physical activity on promoter-specific methylation of genes involved in the redox-status and disease progression: A longitudinal study on post-surgery female breast cancer patients undergoing medical treatment. Redox Biol. 2024 Apr;70:103033. doi: 10.1016/j.redox.2024.103033.

Lisi V, Moulton C, Fantini C, Grazioli E, Guidotti F, Sgrò P, Dimauro I, Capranica L, Parisi A, Di Luigi L, Caporossi D. Steady-state redox status in circulating extracellular vesicles: A proof-of-principle study on the role of fitness level and short-term aerobic training in healthy young males. Free Radic Biol Med. 2023 Aug 1;204:266-275. doi: 10.1016/j.freeradbiomed.2023.05.007.

Lisi V, Senesi G, Bertola N, Pecoraro M, Bolis S, Gualerzi A, Picciolini S, Raimondi A, Fantini C, Moretti E, Parisi A, Sgrò P, Di Luigi L, Geiger R, Ravera S, Vassalli G, Caporossi D, Balbi C. Plasma-derived extracellular vesicles released after endurance exercise exert cardioprotective activity through the activation of antioxidant pathways. Redox Biol. 2023 Jul;63:102737. doi: 10.1016/j.redox.2023.102737.

Moretti E, Cerulli C, Grazioli E, Mauri C, Broccatelli M, De Bellonia S, Tranchita E, Minganti C, Sacchetti M, Parisi A: Osteoporosis prevention in the workplace: the “Happy Bones” protocol. Med Sport 2023;76:228-42. DOI: 10.23736/S0025-7826.23.04291-6.

Cerulli C, Moretti E, Parisi A, Tranchita E, Di Lauro M, Minganti C, Perrone MA, Murri A, Greco F, Marrone G, Noce A, Grazioli E. Correlation between physical activity, nutritional intake, and osteoporosis in postmenopausal women: a preliminary evaluation. Eur Rev Med Pharmacol Sci. 2023 Jun;27(12):5822-5830. doi: 10.26355/eurrev_202306_32821. PMID: 37401319.

Moulton C, Grazioli E, Antinozzi C, Fantini C, Cerulli C, Murri A, Duranti G, Ceci R, Vulpiani MC, Pellegrini P, Nusca SM, Cavaliere F, Fabbri S, Sgrò P, Di Luigi L, Caporossi D, Parisi A, Dimauro I. Online Home-Based Physical Activity Counteracts Changes of Redox-Status Biomarkers and Fitness Profiles during Treatment Programs in Postsurgery Female Breast Cancer Patients. Antioxidants (Basel). 2023 May 22;12(5):1138. doi: 10.3390/antiox12051138. PMID: 37238004; PMCID: PMC10215480.

Parisi A, Mauri C, Tranchita E, Beltrami G, Scorcu M, Cerulli C, Grazioli E. Phytonutrients and weight control: the role of polyphenols. Med Sport 2023;76:6-31. DOI: 10.23736/S0025-7826.23.04256-4

Grazioli E, Muri A, Cerulli C, Moretti E, Tranchita E, Bozzetti F, Parisi A. Do people meet the global recommended level of physical activity? An investigation in Northern Italy. Med Sport 2023 December;76(4):545-56 DOI: 10.23736/S0025-7826.23.04376-4

di Cagno A, Buonsenso A, Centorbi M, Manni L, Di Costanzo A, Casazza G, Parisi A, Guerra G, Calcagno G, Iuliano E, Soligo M, Fiorilli G; WB-EMS Parkinson’s Group. Whole body-electromyostimulation effects on serum biomarkers, physical performance and fatigue in Parkinson’s patients: A randomized controlled trial. Front Aging Neurosci. 2023 Feb 9;15:1086487. doi: 10.3389/fnagi.2023.1086487.

Grazioli E, Cerulli C, Tranchita E, Moretti E, Mauri C, Broccatelli M, De Bellonia S, Abalașei BA, Dumitru IM, Moraru CE, Iacob RM, Blancafort-Alias S, González AI, Riau ÀD, Giménez I Sanz A, Ramos GI, Pekel HA, Altunsoy M, Ozkan S, Dikmen AU, Sacchetti M, Parisi A. Dropout and compliance to physical exercise in menopausal osteopenic women: the European “happy bones” project. Front Sports Act Living. 2023 Jun 27;5:1221409. doi: 10.3389/fspor.2023.1221409.

Noce A, Tranchita E, Marrone G, Grazioli E, Di Lauro M, Murri A, Vanni G, Della Morte Canosci D, Di Daniele N, Parisi A, Tesauro M, Cerulli C. The possible role of physical activity in the modulation of gut microbiota in chronic kidney disease and its impact on cardiovascular risk: a narrative review. Eur Rev Med Pharmacol Sci. 2023 Apr;27(8):3733-3746. doi: 10.26355/eurrev_202304_32172. PMID: 37140322.

Lenzi FR, Tranchita E, Grazioli E, Cerulli C, Esposito V, Coppola G, Moretti E, Mauri C, Minganti C, Parisi A. Performing Group-Based Physical Activity (Gbpa) in the Work-Place: Survey and Sociological Considerations of the “Happy Bones” Project. Sustainability. 2023; 15(1):480. https://doi.org/10.3390/su15010480

Murri A, Vitucci D, Tranchita E, Grazioli E, Gori S, Modena A, Turazza M, Filippini R, Galeazzi S, Verzè M, Frittelli P, Corsi DC, Nicolis F, Parisi A, Cerulli C. “OPERATION PHALCO”-Adapted Physical Activity for Breast Cancer Survivors: Is It Time for a Multidisciplinary Approach? Cancers (Basel). 2022 Dec 21;15(1):34. doi: 10.3390/cancers15010034.