Antinozzi Cristina

Ruolo Accademico: 

Ricercatore Universitario

Area Scientifica: 

Bio-medico

(SSD) Settore Scientifico Disciplinare: 

MED/13

Dipartimento di Scienze Motorie Umane e della Salute - Sezione: 

Scienze della Salute

Recapiti: 

P.zza Lauro de Bosis 15, 00135 Roma

tel. 0636733543

Ricevimento: 

per appuntamento

Curriculum: 

         

Personal Information

 

 

Name

ANTINOZZI Cristina

 

Address

 

 

Phone

0636733543 

 

E-mail

cristina.antinozzi@uniroma4.it

 

citizenship

ITA

 

Date of Birthday

07/08/1983

 

 

Qualifications

 

 

Date of completion

15/12/2011

 

Qualification

obtained

P.h.D.

 

Thesis title

Study of the molecular mechanisms underlying double strand breaks repair during male mouse meiosis

 

Ph.D. title

SCIENCES AND BIOTECHNOLOGIES OF REPRODUCTION AND DEVELOPMENT

 

Name and address of institution

University of ROME "Tor Vergata" - Via O. Raimondo,18 Loc. La Romanina - ROMA

 
     

 

Date of completion

01/10/2008

 

Qualification

obtained

Specialized degree / master degree

 

 Vote

110 cum laude

 

Thesis title

Ruolo fisiologico dell'interazione tra la catena leggera 1 della dineina e la proteina AMBRA1 nell'autofagia  (Physiological role of the interaction between light chain 1 of dinein and AMBRA1 protein in autophagy)

 

Degree class

6/S Degree in biology specialist degrees

 

Name and address of institution

University of ROME "Tor Vergata" - Via O. Raimondo,18 Loc. La Romanina - ROMA

 

Experiences

 

 

Time

01/10/2015 – to date

 

Qualification

Researcher (art. 24 c.3-a L. 240/10) Principal Investigator-Scientific Independence of young Researchers (SIR)

 

Name and address of institution

University of ROMA "Foro Italico" - Piazza Lauro de Bosis, 15 - ROMA

 

Struttura

Dip. L.240/2010 Movement, Human and Health Sciences

 

Time

26/02/2015 - 25/05/2015

 

Qualification

Professional Consultant

 

Activity carried out

Professional performance assignment for the development of: gene expression analysis of bone and mesenchymal cell lines subjected to proliferative and / or differential stimuli

 

Name and address of institution

University of ROME "La Sapienza" - P.zza Aldo Moro, 5 - ROMA

 

Time

01/04/2014 - 31/03/2015

 

Position

Post Doc Research Fellow

 

Name and address of institution

University of ROME "Foro Italico" - Piazza Lauro de Bosis, 15 - ROMA

 

Time

01/04/2013 - 31/03/2014

 

Position

Post Doc Research Fellow

 

Name and address of institution

University of ROME "Foro Italico" - Piazza Lauro de Bosis, 15 - ROMA

 

Time

01/04/2012 - 31/03/2013

 

Position

Post Doc Research Fellow

 

Name and address of institution

University of ROME "Foro Italico" - Piazza Lauro de Bosis, 15 - ROMA

 

Time

01/11/2008 - 31/10/2011

 

Position

P.h.D student

 

Name and address of institution

University of ROME "Tor Vergata" - Via O. Raimondo,18 Loc. La Romanina - ROMA

 

                  Ph.D. title

SCIENCES AND BIOTECHNOLOGIES OF REPRODUCTION AND DEVELOPMENT

 

TECHNICAL COMPETENCE

Mammalian cell cultures, primary germ cells culture, cell cycle stage

synchronization methods, transfection of siRNAs (small interfering RNA) and

DNA constructs in mammalian cell cultures; fluorescence microscopy and

analysis of subcellular structures by immunofluorescence,

immunoistochemestry.

Protein extraction from mammalian cells, dosage of proteins,

spectrophotometry, densitometry, ELISA assay, Bio-Plex Luminex Technology,

electrophoresis of proteins in SDS/acrylamide gel, western immunoblotting,

immunoprecipitation and analysis of protein complexes from mammalian cells.

Nucleic acids extraction, PCR, RT-PCR, southern blotting, cloning basal

techniques.

Experience in mouse transgenesis and genomics

 

Prizes and awards

 

 

Prize/award

Oral Communication SIR 2016 (2016)

 

by

Società italiana di Reumatologia

 

Prize/award

Golden Communication SIAMS 2014 (2014)

 

by

Società italiana di andrologia e medicina della sessualità (SIAMS)

 

Prize/award

Abstract Award XI congresso nazionale SIAMS (2014)

 

by

SIAMS

 

Prize/award

poster award (2013)

 

by

Menarini

 

Prize/award

"Sebastiano e Rita Raeli" Award (2009)

 

By

University of Roma Tor Vergata

 

fellow

Principal Investigator-Scientific Independence of young Researchers (SIR)

 

Name and address of institution

University of rome foro italico, Italy

 

 

Curriculum Scientifico: 

Testosterone-mediated activation of androgenic signaling sustains in vitro the transformed and radioresistant phenotype of rhabdomyosarcoma cell lines. Silvia Giannattasio, Francesca Megiorni, Valentina Di Nisio, Andrea Del Fattore, Rosaria Fontanella, Simona Camero, Cristina Antinozzi, Claudio Festuccia, Giovanni Luca Gravina, Sandra Cecconi, Carlo Dominici, Luigi Di Luigi, Carmen Ciccarelli, Paola De Cesaris, Anna Riccioli, Bianca Maria Zani, Andrea Lenzi, Richard G Pestell, Antonio Filippini, Clara Crescioli, Vincenzo Tombolini, Francesco Marampon. Accepted for publication by the Journal Endocrinological Investigation, May 2018.

Association of circulating CXCL10 and CXCL11 with systemic sclerosis. Clara Crescioli, Clarissa Corinaldesi, Valeria Riccieri, Valeria Raparelli, Massimiliano Vasile, Francesco Del Galdo, Guido Valesini, Andrea Lenzi, Stefania Basili, Cristina Antinozzi. Accepted on Annals of Rheumatic Diseases April 2018

H2AFX and MDC1 promote maintenance of genomic integrity in male germ cells.Testa E, Nardozi D, Antinozzi C, Faieta M, Di Cecca S, Caggiano C, Fukuda T, Bonanno E, Zhenkun L, Maldonado A, Roig I, Di Giacomo M, Barchi M. J Cell Sci. 2018 Feb 7. pii: jcs.214411.

The phosphodiesterase 5 inhibitor tadalafil regulates lipidic homeostasis in human skeletal muscle cell metabolism. Marampon F*, Antinozzi C*, Corinaldesi C, Vannelli GB, Sarchielli E, Migliaccio S, Di Luigi L, Lenzi A, Crescioli C. Endocrine. 2017 Aug 7. doi: 10.1007/s12020-017-1378-2.

Testosterone insulin-like effects: an in vitro study on the short-term metabolic effects of testosterone in human skeletal muscle cells. Antinozzi C, Marampon F, Corinaldesi C, Vicini E, Sgrò P, Vannelli GB, Lenzi A, Crescioli C, Di Luigi L. J Endocrinol Invest. 2017 May 15. doi: 10.1007/s40618-017-0686-y. [

Vitamin D in autoimmune rheumatic diseases: A view inside gender differences. Vasile M, Corinaldesi C, Antinozzi C, Crescioli C. Pharmacol Res. 2017 Mar;117:228-241. doi: 10.1016/j.phrs.2016.12.038.

Potential role for the VDR agonist elocalcitol in metabolic control: Evidences in human skeletal muscle cells. Antinozzi C, Corinaldesi C, Giordano C, Pisano A, Cerbelli B, Migliaccio S, Di Luigi L, Stefanantoni K, Vannelli GB, Minisola S, Valesini G, Riccieri V, Lenzi A, Crescioli C. J Steroid Biochem Mol Biol. 2017 Mar;167:169-181. doi: 10.1016/j.jsbmb.2016.12.010. Epub 2016 Dec 29.

Phosphodiesterase Type 5 Inhibitor Sildenafil Decreases the Proinflammatory Chemokine CXCL10 in Human Cardiomyocytes and in Subjects with Diabetic Cardiomyopathy. Di Luigi L, Corinaldesi C, Colletti M, Scolletta S, Antinozzi C, Vannelli GB, Giannetta E, Gianfrilli D, Isidori AM, Migliaccio S, Poerio N, Fraziano M, Lenzi A, Crescioli C. Inflammation. 2016 Jun;39(3):1238-52. doi: 10.1007/s10753-016-0359-6.

The vitamin D receptor agonist BXL-01-0029 as a potential new pharmacological tool for the treatment of inflammatory myopathies. Di Luigi L, Sottili M, Antinozzi C, Vannelli GB, Romanelli F, Riccieri V, Valesini G, Lenzi A, Crescioli C. PLoS One. 2013 Oct 30;8(10):e77745. doi: 10.1371/journal.pone.0077745. eCollection 2013.